Science




I've spent over a decade on the cutting-edge weight loss research, and science continues to reveal the one true key to dropping 4 to 9 lbs. of belly fat every week and keeping it off for life: avoid hidden sugar. That's why I believe true fitness - true health - must begin in the kitchen.



The Science
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Mayo Clinic Staff. “Belly Fat in Women: How to Keep it Off.” April 2007. http://www.mayoclinic.com/health/belly-fat/WO00128

Arver, S. “Testosterone and the Metabolic Syndrome.” Journal of Men’s Health. 5 (2008):S7–S10.

Escobar-Morreale, HF, JL San Millán. “Abdominal adiposity and the polycystic ovary syndrome.” Trends in Endocrinology & Metabolism. 18 (2007):266–272.

Fontana L, JC Eagon, ME Trujillo, et al. “Visceral Fat Adipokine Secretion Is Associated With Systemic Inflammation in Obese Humans.” Diabetes. 56 (2007):1010–1013.

Forouhi, NG, N Sattar, PM McKeigue. “Relation of C-reactive protein to body fat distribution and features of the metabolic syndrome in Europeans and South Asians.” International Journal of Obesity and Related Metabolic Disorders. 25 (2001):1327–31.

Haffner SM, RA Valdez, MP Stern, et al. “Obesity, body fat distribution and sex hormones in men.” International Journal of Obesity and Related Metabolic Disorders. 17 (1993):643–9.

Janssen, I, PT Katzmarzyk, R Ross. “Waist circumference and not body mass index explains obesity-related health risk.” American Journal of Clinical Nutrition. 79 (2004):379–384.
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Rebuffé-Scrive M, P Mårin, P Björntorp. “Effect of testosterone on abdominal adipose tissue in men.” International Journal of Obesity. 15 (1991):791–5.

Resnick, HE, EA Carter, M Aloia, et al. “Cross-sectional relationship of reported fatigue to obesity, diet, and physical activity: results from the third national health and nutrition examination survey.” Journal of Clinical Sleep Medicine. 2 (2006):163–9.
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Singh, D. “Waist-to-hip ratio and judgment of attractiveness and healthiness of female figures by male and female physicians.” International Journal of Obesity and Related Metabolic Disorders. 18 (1994):731–7.
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Zhang C, KM Rexrode, RM van Dam, et al. “Abdominal obesity and the risk of all-cause, cardiovascular, and cancer mortality: sixteen years of follow-up in US women.” Circulation. 117 (2008):1658–67.
“Eat any sugar alcohol lately?” Yale-New Haven Nutrition Advisor. March 2005. http://www.ynhh.com/online/nutrition/advisor/sugar_alcohol.html.

Abou-Donia, MB, EM El-Masry, AA Abdel-Rahman, et al. “Splenda Alters Gut Microflora and Increases Intestinal P-Glycoprotein and Cytochrome P-450 in Male Rats.” Journal of Toxicology and Environmental Health. Part A 71 (2008):1415–1429.
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Deardorff, J. “Agave provokes a bitter debate as a sweetener.” Chicago Tribune. March 23, 2008.
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Gordon, ES, M Goldgerg, GJ Chosy. “A New Concept in the Treatment of Obesity.” The Journal of the American Medical Association. 186 (1963):50–60.

Higginbotham, S, ZF Zhang, IM Lee, et al. “Dietary Glycemic Load and Risk of Colorectal Cancer in the Women’s Health Study.” Journal of the National Cancer Institute. 96 (2004):229–233.
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Larsson, SC, L Bergkvist, A Wolk. "Consumption of sugar and sugar-sweetened foods and the risk of pancreatic cancer in a prospective study." American Journal of Clinical Nutrition. 84 (2006):1171-1176.
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Maher, TJ, RJ Wurtmant. “Possible Neurologic Effects of Aspartame, a Widely Used Food Additive.” Environmental Health Perspectives. 75 (1987):53–57.

Mattila, PT, M Knuuttila, LE Svanberg, et al. “Beneficial effects of dietary xylitol on mineralized and collagenous tissues.” Current Topics in Neutraceutical Research. 1 (2003).
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Passmore, R, YE Swindells. “Observations on the respiratory quotients and weight gain of man after eating large quantity of carbohydrate.” British Journal of Nutrition. 17 (163):331–339.
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Savita, SM, K Sheela, S Sunanda, et al. “Health Implications of Stevia Rebaudiana.” Journal of Human Ecology. 15 (2004):191–194.
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Additional Research
Barclay L. “Waist Girth Predicts Cardiovascular Risk Better Than BMI.” Medscape Medical News. September 23, 2002.
Barzilai, N, J Wang, D Massilon, et al. “Leptin Selectively Decreases Visceral Adiposity and Enhances Insulin Action.” The Journal of Clinical Investigation. 100 (1997):3105–3110.
Basciano H, L Federico, K Adeli, et al. “Fructose, insulin resistance, and metabolic dyslipidemia.” Nutrition & Metabolism. 2 (2005):5.

Behan KJ, J Mbizo. “The Relationship Between Waist Circumference and Biomarkers for Diabetes and CVD in Healthy Non-Obese Women.” Laboratory Medicine. 38 (2007):422–427.
Bergman RN, SP Kim, IR Hsu, et al. “Abdominal Obesity: Role in the Pathophysiology of Metabolic Disease and Cardiovascular Risk.” American Journal of Medicine. 120 (2007):S3–S8.
Bergman RN, SP Kim, KJ Catalano, et al. “Why Visceral Fat is Bad: Mechanisms of the Metabolic Syndrome.” Obesity. 14 (2006):16S–19S.

Beyer, PL, EM Caviar, and RW McCallum. “Fructose Intake at Current Levels in the United States May Cause Gastrointestinal Distress in Normal Adults.” Journal of the American Dietetic Association. 105 (2005):1559–66.
Bjørbæk, C, BB Kahn. “Leptin Signaling in the Central Nervous System and the Periphery.” Recent Progress in Hormone Research. 59 (2004):305–331.

Buss, D. “Strategies of Human Mating.” Psychological Topics. 15 (2006):239–260.
Cleave TL. The Saccharine Disease. New Canaan, CT: Keats Publishing, August 1975.
Cohen, PG. “Obesity in men: The hypogonadal-estrogen receptor relationship and its effect on glucose homeostasis.” Medical Hypotheses. 70 (2008):358–360.
Cordain L, SB Eaton, A Sebastian, et al. “Origins and evolution of the Western diet: health implications for the 21st century.” American Journal of Clinical Nutrition. 81 (2005):341–354.
Costello, D. “The Price of Obesity.” Los Angeles Times. April 1, 2005.
Demetra DC, PP Jones, AE Pimentel, et al. “Increased abdominal-to-peripheral fat distribution contributes to altered autonomic-circulatory control with human aging.” The American Journal of Physiology - Heart and Circulatory Physiology. 287 (2004):H1530–H1537.
Diamant M, JL Hildo, MA van de Ree, et al. “The Association between Abdominal Visceral Fat and Carotid Stiffness Is Mediated by Circulating Inflammatory Markers in Uncomplicated Type 2 Diabetes.” The Journal of Clinical Endocrinology & Metabolism. 90 (2005):1495–1501.
Ellwood M. “Fall’s Fashion Makes the Waist More Important Than Ever.” New York Daily News. October 4, 2007.
Fisher ML, M Voracek. “The shape of beauty: determinants of female physical attractiveness.” Journal of Cosmetic Dermatology. 5 (2006):190–4.

Fung, TT, V Malik, KM Rexrode, et al. “Sweetened beverage consumption and risk of coronary heart disease in women.” American Journal of Clinical Nutrition. 89 (2009):1037–1042.
Gosnell M. “Killer Fat.” Discover. February 2007.
Hesketh, K, E Waters, J Green, et al. “Healthy Eating, activity and obesity prevention: a qualitative study of parent and child perceptions in Australia.” Health Promotion International. 20 (2005):19–26.
Katcher, HI, RS Legro, AR Kunselman, et al. “The Effects of a Whole Grain-Enriched Hypocaloric Diet on Cardiovascular Disease Risk Factors in Men and Women With Metabolic Syndrome.” American Journal of Clinical Nutrition. 87 (2008):79–90.
Krajcovicová-Kudlácková, M, Kebeková, R Schinzel, et al. “Advanced Glycation End Products and Nutrition.” Physiology Research. 51 (2002):313–316.

Mulligan, K, K Hootan, JM Schwarz, et al. “The Effects of Recombinant Human Leptin on Visceral Fat, Dyslipidemia, and Insulin Resistance in Patients with Human Immunodeficiency Virus-Associated Lipoatrophy and Hypoleptinemia.” Journal of Clinical Endocrinology & Metabolism. 94 (2009):1137–1144.
Öhman MK, Y Shen, CI Obimba, et al. “Visceral Adipose Tissue Inflammation Accelerates Atherosclerosis in Apolipoprotein E–Deficient Mice.” Circulation. 117 (2008):798–805.
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Reitzes, D. “Self and Health: Factors Influencing Self-Esteem and Functional Health.” Paper presented at the annual meeting of the American Sociological Association, Marriott Hotel, Loews Philadelphia Hotel, Philadelphia, PA, Aug 12, 2005.
Rosch PJ. “All Obesity Is Not Created Equal.” Science. 301 (2003):1325.
Sanches FMR, CM Avesani, MA Kamimura, et al. “Waist Circumference and Visceral Fat in CKD: A Cross-sectional Study.” American Journal of Kidney Diseases. 52 (2008):66–73.
Stanhope, K, P Havel. “Fructose Consumption: Considerations for Future Research on Its Effects on Adipose Distribution, Lipid Metabolism, and Insulin Sensitivity in Humans.” The Journal of Nutrition. 139 (2009):1236S–1241S.
Stanhope, KL, PJ Havel. “Fructose Consumption: Potential Mechanisms for its Effects to Increase Visceral Adiposity and Induce Dyslipidemia and Insulin Resistance.” Current Opinion in Lipidology. 19 (2008):16–24.
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Teff, KL, SS Elliott, M Tschop, et al. “Dietary Fructose Reduces Circulating Insulin and Leptin, Attenuates Postprandial Suppression of Ghrelin, and Increases Triglycerides in Women.” The Journal of Clinical Endocrinology & Metabolism. 89 (2004):2963–2972.
Tilg H, AR Moschen. “Adipocytokines: mediators linking adipose tissue, inflammation and immunity.” Nature Reviews Immunology. 6 (2006)772–783.

Tracy RP. “Is Visceral Adiposity the ‘Enemy Within’?” Arteriosclerosis, Thrombosis, and Vascular Biology. 21 (2001):881–883.
Wang Y, MA Beydoun, L Liang, et al. “Will all Americans become overweight or obese? Estimating the progression and cost of the US obesity epidemic.” Obesity. 16 (2008):2323–30.
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Zumoff B, GW Strain, LK Miller, et al. “Plasma free and non-sex-hormone-binding-globulin-bound testosterone are decreased in obese men in proportion to their degree of obesity.” Journal of Clinical Endocrinology & Metabolism. 71 (1990):929–931.


1 comment:

  1. Lipocut 120 MG Capsule is an antiobesity preparations that helps in reducing the weight of obese patients. Take this medicine with each meal containing fat. Proper diet and exercise are necessary to control weight. Multivitamins are recommended while taking this preparation.Take Lipocut 120 MG Capsule with the high-fat meal. Do not take this medicine if you skip the meal or if the meal contains no fat. Low-calorie, low-fat diet, and exercise are needed to control weight.

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